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Flow Cytometry

Section Director: Jason Kurzer, M.D.
Operations Manager: Cynthia Samson, MA, MT(ASCP) SH, CLS

General Information
The Stanford Clinical Flow Cytometry laboratory offers a comprehensive diagnostic test menu, including leukemia/lymphoma immunophenotyping, CD34+ stem cell quantitation, lymphocyte subset analysis, paroxysmal nocturnal hemoglobulinuria (PNH) screen and Sézary syndrome.

The most common indications include suspected acute leukemia, non-Hodgkin lymphoma, chronic lymphoid leukemias, myeloma or plasmacytoma, an unexplained lymphocytosis, or any atypical mononuclear cell population of unclear origin in blood, bone marrow, body fluids or lymphoid tissue. In addition, patients with cytopenias of unclear etiology may benefit from flow cytometric immunophenotyping, as some hematolymphoid neoplasms (hairy cell leukemia, LGL leukemia) may have relatively subtle peripheral blood or bone marrow findings. While flow cytometric immunophenotyping is generally useful for evaluating most hematolymphoid neoplasms, it is not recommended in cases of suspected myeloproliferative disorder where blasts are not increased, or in bone marrow staging for Hodgkin lymphoma.

TO SEND A SPECIMEN FOR CONSULTATION

TESTS: Select a test to view Test Description & Clinical IndicationsTEST CODES:
Select a Test Code to view Test Specimen Collection Instructions
CD34 PANEL, BLOODCD34
CD34 PANEL, BONE MARROWBMCD34
CD34 PANEL, FLUIDFCD34
CD4-CD8 PANEL, BLOODC4C8
EMA (EOSIN-5-MALEIMIDE) BY FLOW CYTOMETRYEMA
IMMUNOPHENOTYPING BY FLOW CYTOMETRYFCPATH
PAROXYSMAL NOCTURNAL HEMOGLOBINURIA SCREEN (PNH) SCREEN PATH13/FCPATHPATH13/FCPATH
SÉZARY/T-CELL PANELPATH18
T SUBSETS AND B LYMPHS, FLUIDFTBLYM
T SUBSETS AND B LYMPHS, WHOLE BLOODTBLYM

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Hours
Specimens are accepted 24 hours a day, seven days a week, except as noted in test specimen requirements.

Consultation Services
Comprehensive review is available, which indicates that a pathologist will review the material (such as bone marrow or peripheral blood) to give a morphologic assessment. Based on that evaluation, the pathologist will recommend the appropriate ancillary tests (such as flow cytometry, cytogenetics or molecular genetics) to completely assess the sample. These additional tests will only be performed after consulting with the ordering physician. Stanford’s expert hematopathologists will recommend only the tests necessary to adequately evaluate the sample.

"Morphologic evaluation" indicates that a Stanford hematopathologist will review and report on the morphologic features of the sample in addition to the other tests ordered. Morphologic evaluation is performed automatically on specimens submitted for leukemia/lymphoma immunophenotyping and PNH screening. If additional testing (such as molecular testing) is needed after the initial morphologic review, you would be
contacted immediately to consider ordering those studies on the original sample.

For consultation services please call Customer Services at 1-877-717-3733 and request the Flow Cytometry Laboratory.


 
 


 
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