Stanford Health Care
About Stanford Clinical LaboratoryLicensureContact Us

Home
Test Directory

Test Requisitions Specimen Collection
Critical Values
Administrative Department
Clinical DepartmentsDepartment of PathologyEsoteric DepartmentsFeatured Services



MUCOPOLYSACCHARIDES, TLC, URINE

Test Code: MPSTLC
Description:

This screening test is used in the evaluation of patients suspected of having one of the mucopolysaccharidoses, including Hurler (MPS IH), Scheie (MPS IS), Hunter (MPS II), Sanfilippo (MPS III), Morquio (MPS IV), Marteaux-Lamy (MPS VI) and Sly (MPS VII) syndromes. Mucopolysaccharides (MPS) are extracted from urine and fractionated using high-performance thin-layer chromatography (TLC). Specific mucopolysaccharides including keratan, heparan, dermatan and chondroitin sulfates are visualized following staining with toluidine blue. Abnormal results should be followed up with specific diagnostic enzyme testing. Clinical history should be provided to the laboratory for optimal interpretation of results.

 


 
 


 
Home | About Stanford Clinical Laboratories | Careers | Contact Us | Legal Notices & Disclaimer