Immunohistochemistry
A Diagnostic Modality Supporting Anatomic Pathology
The Stanford Immunodiagnosis Laboratory provides clinical testing on surgical, cytology, and frozen muscle biopsy specimens for diagnostic, prognostic and therapeutic biomarkers. We offer an extensive list of immunohistochemical and in-situ hybridization assays that detect tumor markers, enzymes and infectious agents.
Immunohisto chemistry
Special Stains
Enzyme Histochemistry Stains
Insitu Hybridization Stains
Neuropath Frozen
Immunohistochemistry Stains
Special Stains
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1
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1
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1
AB |
1
Alcian Blue Stain |
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1
AFB |
1
AFB Stain |
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1
Alcian Blue |
1
Alcian blue-PAS |
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1
Bielschovsky |
1
Bielschovsky |
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1
Colloidal iron |
1
Colloidal iron |
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1
Congo Red |
1
Congo Red for Amyloid |
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1
CU |
1
Copper |
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1
EVG |
1
Elastic Van Gieson |
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1
FE |
1
Iron Stain |
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1
FITE |
1
Fite Stain |
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1
GIEM |
1
Giemsa |
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1
GMS |
1
GMS Stain |
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1
Gram |
1
Gram |
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1
Jones |
1
Jones Stain |
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1
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1
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|---|---|
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1
KB |
1
Kluver-Barrera Stain |
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1
LFB |
1
LFB |
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1
Melanin |
1
Melanin |
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1
Mucicarmine |
1
Mucicarmine |
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1
Oil-red-O |
1
Oil-red-O |
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1
PAS |
1
PAS Stain |
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1
PASd |
1
PAS with diastase |
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1
PASdf |
1
PAS Stain/Frozen tissue with distase |
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1
Reticulin |
1
Reticulin |
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1
Toluidine Blue |
1
Toluidine Blue |
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1
Trichrome |
1
Trichrome Stain |
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1
von Kossa |
1
von Kossa |
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1
Warthin Starry |
1
Warthin Starry |
Enzyme Histochemistry
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1
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1
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1
ACIDPH |
1
Acid Phosphatase |
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1
AD |
1
Adenylate Deaminase |
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1
ALKPH |
1
Alkaline Phosphastase |
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1
ATP4.3 |
1
ATPase 4.3 |
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1
ATP4.6 |
1
ATPase 4.6 |
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1
ATP9.4 |
1
ATPase 9.4 |
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1
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1
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|---|---|
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1
COX-SDH |
1
Cytochrome Oxidase |
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1
EST NP |
1
Esterase for NP |
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1
MYOPH |
1
Myophoshorylase |
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1
NADH |
1
NADH-TR |
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1
PFK |
1
Phoshofructokinase Histochemical Stain |
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1
SDH |
1
SDH |
Insitu Hybridization Stains
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1
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1
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|---|---|
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1
Albumin ISH |
1
Albumin ISH, RNAscope ISH |
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1
CSF1 ISH |
1
CSF1, colony stimulating factor, macrophages, CSF1-COL6A3 fusion, RNAscope ISH |
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1
CovSpike ISH |
1
SARS Cov2 spike protein RNAscope ISH |
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1
HER2 Chr17 Dual ISH/ HER2 DISH |
1
Insitu Hybridization for Her2neu- breast, ErbB2 |
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1
HPV HIGH RISK ISH |
1
Human Papilloma Virus, HPV 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73 and 82, E6/E7 mRNA, RNAscope ISH |
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1
HPV LOW RISK ISH |
1
Human Papilloma Virus, HPV, HPV6,11,40,42,43,44, RNAscope ISH |
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1
ISH EBER |
1
Insitu Hybridization for Eber |
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1
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1
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1
ISH Kappa |
1
Insitu Hybridization for Kappa |
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1
ISH Lambda |
1
Insitu Hybridization for Lambda |
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1
MERKEL PV ISH |
1
MerkelPV ISH, Merkel cell polyomavirus, RNAscope ISH (V-MCPyV-LT-ST-Ag-O1), RNAscope ISH |
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1
MYB ISH |
1
myb RNAscope ISH |
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1
PDGFB ISH |
1
PDGFB ISH, platelet derived growth factor beta, RNAscope ISH |
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1
TRIM63 ISH |
1
MITF, TFE3, ASPS, RNAscope ISH |
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1
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1
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Neuropath Frozen Tissue Stains
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1
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1
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|---|---|
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1
Alpha-sarco |
1
Alpha sarcoglycanopathy dystrophy LGMD 2D frozen muscle 17q21 |
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1
Beta-sarco |
1
Beta sarcoglycanopathy dystrophy LGMD 2E frozen muscle 4q12 |
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1
Delta-sarco |
1
Delta-sarco Delta sarcoglycanopathy dystrophy LGMD 2F frozen muscle 5q33.3 |
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1
Dysferlin |
1
Dembrane repair, Myoshi, LGMD2B, distal myopathy, frozen muscle 2p12 |
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1
Dystro C 6c5 |
1
Dystrophinopathy C-terminus clone 6C5 frozen muscle dystrophy |
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1
Dystro N 12B |
1
Dystrophinopathy N-terminus clone 12B2 frozen muscle dystrophy |
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1
Dystro N 4c7 |
1
Dystrophinopathy N-terminus clone 4c7 frozen muscle dystrophy |
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1
Dystro R-6a9 |
1
Dystrophinopathy rod domain clone 6a9 frozen muscle dystrophy |
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1
Dystro R-7g1 |
1
Dystrophinopathy rod domain clone 7g1 frozen muscle dystrophy |
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1
Dystrog IIH6 |
1
Congenital dystrophy CMD alpha dystroglycan frozen muscle IIH6C4 3p21 |
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1
Dystrog VIA4 |
1
Congenital dystrophy CMD alpha dystroglycan frozen muscle VIA4-1 3p21 |
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1
Emerin |
1
Emery-Dreifuss dystrophy 1 EMD1 emerin nuclear frozen muscle Xq28 |
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1
Gamma-sarco |
1
gamma sarcoglycanopathy dystrophy LGMD 2C frozen muscle 13q12.12 |
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1
Laminin a2 |
1
Merosin congenital dystrophy MDC1A laminin alpha2 frozen muscle 6q22 |
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1
Myosin Double |
1
Slow/fast myosin double stain |
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1
Myotilin |
1
Myofibrillar myopathy dystrophy type 1A myotilin frozen muscle 5q31 |
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1
Nestin |
1
Neuroectodermal stem-cell protein neural development filament nestin |
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1
Parvalbumin |
1
Low-mw calcium-binding albumin protein GABA interneurons parvalbumin |
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1
Spectrin |
1
Sarcolemmal cytoskeletal, membrane integrity, dystrophy, frozen muscle |
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1
Utrophin |
1
Sarcolemmal cytoskeletal, increase in dystrophinopathy, frozen muscle |
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1
YAP1 |
1
SHH or WNT pathway activation medulloblastoma YAP-1 YAP1 |
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1
Colloidal iron |
1
Colloidal iron (Special Stain) |
Immunohistochemistry Stains
close Immunohisto chemistry
Special Stains
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1
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1
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|---|---|
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1
AB |
1
Alcian Blue Stain |
|
1
AFB |
1
AFB Stain |
|
1
Alcian Blue |
1
Alcian blue-PAS |
|
1
Bielschovsky |
1
Bielschovsky |
|
1
Colloidal iron |
1
Colloidal iron |
|
1
Congo Red |
1
Congo Red for Amyloid |
|
1
CU |
1
Copper |
|
1
EVG |
1
Elastic Van Gieson |
|
1
FE |
1
Iron Stain |
|
1
FITE |
1
Fite Stain |
|
1
GIEM |
1
Giemsa |
|
1
GMS |
1
GMS Stain |
|
1
Gram |
1
Gram |
|
1
Jones |
1
Jones Stain |
|
1
|
1
|
|---|---|
|
1
KB |
1
Kluver-Barrera Stain |
|
1
LFB |
1
LFB |
|
1
Melanin |
1
Melanin |
|
1
Mucicarmine |
1
Mucicarmine |
|
1
Oil-red-O |
1
Oil-red-O |
|
1
PAS |
1
PAS Stain |
|
1
PASd |
1
PAS with diastase |
|
1
PASdf |
1
PAS Stain/Frozen tissue with distase |
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1
Reticulin |
1
Reticulin |
|
1
Toluidine Blue |
1
Toluidine Blue |
|
1
Trichrome |
1
Trichrome Stain |
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1
von Kossa |
1
von Kossa |
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1
Warthin Starry |
1
Warthin Starry |
close Special Stains
Enzyme Histochemistry
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1
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1
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|---|---|
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1
ACIDPH |
1
Acid Phosphatase |
|
1
AD |
1
Adenylate Deaminase |
|
1
ALKPH |
1
Alkaline Phosphastase |
|
1
ATP4.3 |
1
ATPase 4.3 |
|
1
ATP4.6 |
1
ATPase 4.6 |
|
1
ATP9.4 |
1
ATPase 9.4 |
|
1
|
1
|
|---|---|
|
1
COX-SDH |
1
Cytochrome Oxidase |
|
1
EST NP |
1
Esterase for NP |
|
1
MYOPH |
1
Myophoshorylase |
|
1
NADH |
1
NADH-TR |
|
1
PFK |
1
Phoshofructokinase Histochemical Stain |
|
1
SDH |
1
SDH |
close Enzyme Histochemistry Stains
Insitu Hybridization Stains
|
1
|
1
|
|---|---|
|
1
Albumin ISH |
1
Albumin ISH, RNAscope ISH |
|
1
CSF1 ISH |
1
CSF1, colony stimulating factor, macrophages, CSF1-COL6A3 fusion, RNAscope ISH |
|
1
CovSpike ISH |
1
SARS Cov2 spike protein RNAscope ISH |
|
1
HER2 Chr17 Dual ISH/ HER2 DISH |
1
Insitu Hybridization for Her2neu- breast, ErbB2 |
|
1
HPV HIGH RISK ISH |
1
Human Papilloma Virus, HPV 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73 and 82, E6/E7 mRNA, RNAscope ISH |
|
1
HPV LOW RISK ISH |
1
Human Papilloma Virus, HPV, HPV6,11,40,42,43,44, RNAscope ISH |
|
1
ISH EBER |
1
Insitu Hybridization for Eber |
|
1
|
1
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|---|---|
|
1
ISH Kappa |
1
Insitu Hybridization for Kappa |
|
1
ISH Lambda |
1
Insitu Hybridization for Lambda |
|
1
MERKEL PV ISH |
1
MerkelPV ISH, Merkel cell polyomavirus, RNAscope ISH (V-MCPyV-LT-ST-Ag-O1), RNAscope ISH |
|
1
MYB ISH |
1
myb RNAscope ISH |
|
1
PDGFB ISH |
1
PDGFB ISH, platelet derived growth factor beta, RNAscope ISH |
|
1
TRIM63 ISH |
1
MITF, TFE3, ASPS, RNAscope ISH |
|
1
|
1
|
close Insitu Hybridization Stains
Neuropath Frozen Tissue Stains
|
1
|
1
|
|---|---|
|
1
Alpha-sarco |
1
Alpha sarcoglycanopathy dystrophy LGMD 2D frozen muscle 17q21 |
|
1
Beta-sarco |
1
Beta sarcoglycanopathy dystrophy LGMD 2E frozen muscle 4q12 |
|
1
Delta-sarco |
1
Delta-sarco Delta sarcoglycanopathy dystrophy LGMD 2F frozen muscle 5q33.3 |
|
1
Dysferlin |
1
Dembrane repair, Myoshi, LGMD2B, distal myopathy, frozen muscle 2p12 |
|
1
Dystro C 6c5 |
1
Dystrophinopathy C-terminus clone 6C5 frozen muscle dystrophy |
|
1
Dystro N 12B |
1
Dystrophinopathy N-terminus clone 12B2 frozen muscle dystrophy |
|
1
Dystro N 4c7 |
1
Dystrophinopathy N-terminus clone 4c7 frozen muscle dystrophy |
|
1
Dystro R-6a9 |
1
Dystrophinopathy rod domain clone 6a9 frozen muscle dystrophy |
|
1
Dystro R-7g1 |
1
Dystrophinopathy rod domain clone 7g1 frozen muscle dystrophy |
|
1
Dystrog IIH6 |
1
Congenital dystrophy CMD alpha dystroglycan frozen muscle IIH6C4 3p21 |
|
1
Dystrog VIA4 |
1
Congenital dystrophy CMD alpha dystroglycan frozen muscle VIA4-1 3p21 |
|
1
Emerin |
1
Emery-Dreifuss dystrophy 1 EMD1 emerin nuclear frozen muscle Xq28 |
|
1
Gamma-sarco |
1
gamma sarcoglycanopathy dystrophy LGMD 2C frozen muscle 13q12.12 |
|
1
Laminin a2 |
1
Merosin congenital dystrophy MDC1A laminin alpha2 frozen muscle 6q22 |
|
1
Myosin Double |
1
Slow/fast myosin double stain |
|
1
Myotilin |
1
Myofibrillar myopathy dystrophy type 1A myotilin frozen muscle 5q31 |
|
1
Nestin |
1
Neuroectodermal stem-cell protein neural development filament nestin |
|
1
Parvalbumin |
1
Low-mw calcium-binding albumin protein GABA interneurons parvalbumin |
|
1
Spectrin |
1
Sarcolemmal cytoskeletal, membrane integrity, dystrophy, frozen muscle |
|
1
Utrophin |
1
Sarcolemmal cytoskeletal, increase in dystrophinopathy, frozen muscle |
|
1
YAP1 |
1
SHH or WNT pathway activation medulloblastoma YAP-1 YAP1 |
|
1
Colloidal iron |
1
Colloidal iron (Special Stain) |
close Neuropath Frozen
Medical Director
Yasodha Natkunam, MD, PhD
Professor of Pathology
Co-Director, Immunopathology Laboratory
Medical Director
Megan Troxell, MD, PhD
Professor of Pathology Co-Director, Surgical Pathology
Medical Director
Sebastian Fernadez-Pol, MD
Assistant Professor, Pathology
Assistant Director, Stanford Immunopathology Laboratory