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Gastrointestinal & Hepatobiliary Pathology

A Subspecialty Of  Anatomic Pathology

About Gastrointestinal & Hepatobiliary Pathology

Digestive diseases affect 1 in 5 Americans annually – at least 60 million people in the United States each year. Digestive diseases and colonoscopies account for nearly 75 million endoscopic diagnostic procedures across the US annually. The Gastrointestinal & Hepatobiliary Pathology service at Stanford provides comprehensive diagnostic expertise and services relating to the pathology of disorders of the gastrointestinal tract, liver, and pancreas.

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Our Services

Submit a Specimen

Our Faculty

Ancillary Testing

 

Stanford’s Gastrointestinal & Hepatobiliary Pathology Service offers expert diagnosis for wet tissue and consult cases for neoplastic and non-neoplastic diseases of the gastrointestinal tract, liver, biliary tract, and pancreas. Our faculty has expertise in a wide spectrum of clinical specialties, including Barrett’s esophagus, celiac disease, inflammatory bowel disease, and premalignant dysplastic lesions and malignant lesions of the luminal gastrointestinal tract, pancreas, liver, and biliary tract.

 

Consultative Opinions & Case Reviews

Stanford’s Gastrointestinal & Hepatobiliary Pathology Service offers consultative opinions on challenging cases submitted from outside of the Stanford network. These consultations can be utilized to offer expert opinion, answer specific questions, perform corroborative studies for suspected or unusual disease entities, and to confirm diagnoses. This service includes assignment of a specialty pathology fellow to each case for individualized service.

 

Primary Pathology Diagnosis

Stanford’s Gastrointestinal & Hepatobiliary Pathology Service performs gross and microscopic examination and reporting of wet tissue cases. This includes:

  • Complete mapping of gastric cancer in CDH1 germline mutation carriers
  • Second read on all dysplasia diagnoses
  • CAP templates on all malignancies
  • MMR, PDL-1, HER2 IHC and EBV ISH on all gastric cancers
  • MMR, PDL-1, HER2 IHC on all esophageal cancers
  • MMR on all GI and hepatobiliary malignancies
  • Reflex BRAF on all MLH1/PMS2 deficient colorectal cancers
  • HER2 IHC on all metastatic/recurrent colorectal cancers
  • Reflex HER2 FISH for all equivocal HER2 IHC
  • CD117, ANO1 (DOG1), and SDHB (gastric) on all suspected GISTs
  • P16 and when indicated, high-risk HPV ISH on squamous cell carcinoma
  • Chromogranin, synaptophysin, INSM1 and Ki-67 on neuroendocrine tumors
  • P53 and RB1 on suspected neuroendocrine carcinoma
  • Diagnostic tests for pancreatic tumors, including beta-catenin, chymotrypsin, inhibin, etc.
  • Diagnostic tests for liver adenomas

Consult Cases

To submit slides for case review, please fill out a Stanford requisition and include all slides, relevant reports, and ancillary testing materials and reports. If possible, please include a block, as it will greatly speed the finalization of the case should additional testing be necessary. Package all materials securely and send via a padded envelope.

 

Wet Tissue Specimens

Please submit materials in proper transport media. All samples should be labeled with the patient information (name, DOB and one other unique identifier) and sealed in a biohazard bag. 

 

Samples should be shipped or delivered via courier to:

Stanford Surgical Pathology – Consults (slides/blocks only):
Attn: Gastrointestinal Pathology

300 Pasteur Drive, Room H2110
Stanford, CA 94305
Phone: 650-723-7211
Fax: 650-725-7409

Stanford Surgical Pathology – Wet Tissue:
Attn: Gastrointestinal Pathology

3375 Hillview Avenue
Palo Alto, CA 94304
Phone: 650-723-7211
Fax: 650-725-7409

 

Gastrointestinal Pathology Requisition

 

New Client Inquiries

To arrange to be set up as a new client, please contact:
ClinOpsContracts@stanfordhealthcare.org.

 

Contact Us

To submit a specimen to Gastrointestinal Pathology, please complete a requisition and send with sample to:

 

Stanford Gastrointestinal & Hepatobiliary Pathology Service

300 Pasteur Drive, Room H2110
Stanford, CA 94305

Phone: 650-723-7211
Fax (650) 725-7409

gipathology@
stanfordhealthcare.org

Do not send patient info to this email.

Medical Director:
Teri Longacre, MD

 

To arrange to be set up as a new client, please contact:
ClinOpsContracts@
stanfordhealthcare.org

 

Download Gastrointestinal Pathology Requisition

SAMPLE SUBMISSION LOGISTICS
For more information on submitting cases, see the links below:

All Requisitions
Download Stanford Requisitions for specimen submission.

Account Set-up
Information on personalized requisitions, supplies, shipping and courier pick-up.

Pricing Inquiries
Pricing inquiries and contract information.

Billing
Billing policies, information and questions.

Results Web Portal
Request access or log-in to our client results portal.

Specimen Collection and Handling
Specifications for Specimen Collection and Handling.

Consult Service FAQ's
Get answers to Frequently Asked Questions.

Teri A. Longacre, MD

Teri A. Longacre, MD

APPOINTMENTS

  • Professor of Pathology, Emerita Kempson Endowed Chair in Surgical Pathology
  • Director, Gastrointestinal-Hepatopancreatobiliary Pathology Service
  • Director, Gastrointestinal-Hepatopancreatobiliary Pathology Fellowship
  • Director, Gynecologic Pathology Service
  • Director, Gynecological Pathology Fellowship

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology
  • Gynecologic and Obstetric Pathology

CONTACT

Email: longacre@stanford.edu
Phone: (650) 498-6460

More information about Teri Longacre:
https://med.stanford.edu/profiles/teri-longacre

Gerald J. Berry, MD

Gerald Berry, MD

APPOINTMENTS

  • Professor of Pathology

 

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Cardiovascular Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology
  • Pulmonary & Thoracic Pathology

CONTACT

Email: gerald.berry@stanford.edu
Phone: (650) 498-4987

More information about Gerald Berry:
https://med.stanford.edu/profiles/gerald-berry

David Bingham, MD

David Bingham, MD

APPOINTMENTS

  • Clinical Assistant Professor, Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology

CONTACT

Phone: (650) 498-4391

More information about David Bingham:
https://med.stanford.edu/profiles/david-bingham

Lawrence Walden Browne, MD

Lawrence Walden Browne, MD

APPOINTMENTS

  • Clinical Assistant Professor of Pathology
    ValleyCare Tri-Valley

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology
  • Medical Liver Pathology

CONTACT

Email: waldenb@stanford.edu
Phone: (925) 416-3404

More information about Lawrence Browne:
https://med.stanford.edu/profiles/lawrence-browne

Gregory Charville, MD, PhD

Gregory Charville, MD, PhD

APPOINTMENTS

  • Associate Professor of Pathology
  • Medical Director, Soft Tissue and Bone Pathology Service
  • Associate Director of Gastrointestinal Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Bone-Soft Tissue Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology

CONTACT

Email: gwc@stanford.edu
Phone: (650) 723-7211

More information about Gregory Charville:
https://med.stanford.edu/profiles/greg-charville

John Higgins, MD

John Higgins, MD

APPOINTMENTS

  • Residency Program Director for Anatomic and Clinical Pathology
  • Professor of Pathology
  • Co-Director, Post-Sophomore Fellowship in Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology
  • Medical Liver Pathology
  • Renal Pathology
  • Transplant Pathology

CONTACT

Email: john.higgins@stanford.edu
Phone: (650) 723-7211

More information about John Higgins:
https://med.stanford.edu/profiles/john-higgins

Maggie Lam, MD

Maggie Lam, MD

APPOINTMENTS

  • Clinical Associate Professor of Pathology
    ValleyCare Medical Center
  • SHC Tri-Valley Director of Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Breast Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology

CONTACT

Email: mmlam@stanford.edu
Phone: (925) 416-3404

More information about Maggie Lam:
https://med.stanford.edu/profiles/maggie-lam

Richard Hildebrandt, MD

Richard Hildebrandt, MD

APPOINTMENTS

  • Clinical Assistant Professor, Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology
  • Obstetric Pathology

CONTACT

Email: rhildey8@stanford.edu
Phone: (650) 723-7211

More information about Richard Hildebrandt:
https://med.stanford.edu/profiles/richard-hildebrandt

Jody Hooper, MD

Donald P. Regula Jr., MD

APPOINTMENTS

  • Director of Autopsy, Director of Research Autopsy Center
  • Associate Professor – University Medical Line, Pathology
  • Member, Stanford Cancer Institute

PRACTICE AREAS

  • Anatomic Pathology
  • Autopsy
  • Gastrointestinal Pathology

CONTACT

Email: jehooper@stanford.edu  

Phone: (650) 723-6265

Jeanne Shen, MD

Jeanne Shen, MD

APPOINTMENTS

  • Assistant Professor of Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Digital Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology

CONTACT

Phone: (650) 723-7211

More information about Jeanne Shen:
https://med.stanford.edu/profiles/jeanne-shen

Serena Tan, MD

Serena Tan, MD

APPOINTMENTS

  • Assistant Professor of Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology
  • Pediatric Pathology

CONTACT

Phone: (650) 723-6111

More information about Serena Tan:
https://med.stanford.edu/profiles/serena-tan

Cindy Wang, MD

APPOINTMENTS

  • Clinical Assistant Professor of Pathology
  • Associate Director of Gastrointestinal-Hepatopancreatobiliary Pathology Fellowship

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology

CONTACT

Email: cwang22@stanford.edu
Phone: (650) 498-4987

More information about Cindy Wang:
https://med.stanford.edu/profiles/252486

Ancillary Testing

Stanford’s Gastrointestinal & Hepatobiliary Pathology Service relies on a suite of ancillary testing offerings to support our expert diagnosis. Learn more about these offerings. Many of these techniques, such as molecular profiling and cytogenetics, can be performed on cytology as well as tissue sections.

 

Immunohistochemistry

Our immunohistochemistry laboratory offers a wide array of antibody-based tests and in situ hybridization assays, which our pathologists select and interpret judiciously to refine their diagnoses.

These assays are validated for paraffin-embedded tissue, including cytology cell blocks. We provide testing for inflammatory myofibroblast tumor (ALK), MMR deficiency, pancreatic acinar cell carcinoma, and SDH deficiency, in addition to all the standard markers in gastrointestinal and hepatobiliary pathology (p53, p16, PDL-1, HER2, etc.). We also offer high-risk HPV in-situ hybridization.

 

Molecular Pathology

Molecular assays can be used for both diagnostic and prognostic purposes as well as for selection of targeted therapies. Stanford’s Solid Tumor Actionable Mutation Panel (STAMP) is validated on cytology specimens and paraffin-embedded tissue. We provide specific tests for various gastrointestinal mesenchymal lesions, including NTRK-rearranged sarcoma.

 

Cytogenetics

Cytogenetic studies are used to assess for chromosomal rearrangements in selected cases.

Our Services

Stanford’s Gastrointestinal & Hepatobiliary Pathology Service offers expert diagnosis for wet tissue and consult cases for neoplastic and non-neoplastic diseases of the gastrointestinal tract, liver, biliary tract, and pancreas. Our faculty has expertise in a wide spectrum of clinical specialties, including Barrett’s esophagus, celiac disease, inflammatory bowel disease, and premalignant dysplastic lesions and malignant lesions of the luminal gastrointestinal tract, pancreas, liver, and biliary tract.

 

Consultative Opinions & Case Reviews

Stanford’s Gastrointestinal & Hepatobiliary Pathology Service offers consultative opinions on challenging cases submitted from outside of the Stanford network. These consultations can be utilized to offer expert opinion, answer specific questions, perform corroborative studies for suspected or unusual disease entities, and to confirm diagnoses. This service includes assignment of a specialty pathology fellow to each case for individualized service.

 

Primary Pathology Diagnosis

Stanford’s Gastrointestinal & Hepatobiliary Pathology Service performs gross and microscopic examination and reporting of wet tissue cases. This includes:

  • Complete mapping of gastric cancer in CDH1 germline mutation carriers
  • Second read on all dysplasia diagnoses
  • CAP templates on all malignancies
  • MMR, PDL-1, HER2 IHC and EBV ISH on all gastric cancers
  • MMR, PDL-1, HER2 IHC on all esophageal cancers
  • MMR on all GI and hepatobiliary malignancies
  • Reflex BRAF on all MLH1/PMS2 deficient colorectal cancers
  • HER2 IHC on all metastatic/recurrent colorectal cancers
  • Reflex HER2 FISH for all equivocal HER2 IHC
  • CD117, ANO1 (DOG1), and SDHB (gastric) on all suspected GISTs
  • P16 and when indicated, high-risk HPV ISH on squamous cell carcinoma
  • Chromogranin, synaptophysin, INSM1 and Ki-67 on neuroendocrine tumors
  • P53 and RB1 on suspected neuroendocrine carcinoma
  • Diagnostic tests for pancreatic tumors, including beta-catenin, chymotrypsin, inhibin, etc.
  • Diagnostic tests for liver adenomas

close Our Services
Submit a Specimen

Consult Cases

To submit slides for case review, please fill out a Stanford requisition and include all slides, relevant reports, and ancillary testing materials and reports. If possible, please include a block, as it will greatly speed the finalization of the case should additional testing be necessary. Package all materials securely and send via a padded envelope.

 

Wet Tissue Specimens

Please submit materials in proper transport media. All samples should be labeled with the patient information (name, DOB and one other unique identifier) and sealed in a biohazard bag. 

 

Samples should be shipped or delivered via courier to:

Stanford Surgical Pathology – Consults (slides/blocks only):
Attn: Gastrointestinal Pathology

300 Pasteur Drive, Room H2110
Stanford, CA 94305
Phone: 650-723-7211
Fax: 650-725-7409

Stanford Surgical Pathology – Wet Tissue:
Attn: Gastrointestinal Pathology

3375 Hillview Avenue
Palo Alto, CA 94304
Phone: 650-723-7211
Fax: 650-725-7409

 

Gastrointestinal Pathology Requisition

 

New Client Inquiries

To arrange to be set up as a new client, please contact:
ClinOpsContracts@stanfordhealthcare.org.

 

Contact Us

To submit a specimen to Gastrointestinal Pathology, please complete a requisition and send with sample to:

 

Stanford Gastrointestinal & Hepatobiliary Pathology Service

300 Pasteur Drive, Room H2110
Stanford, CA 94305

Phone: 650-723-7211
Fax (650) 725-7409

gipathology@
stanfordhealthcare.org

Do not send patient info to this email.

Medical Director:
Teri Longacre, MD

 

To arrange to be set up as a new client, please contact:
ClinOpsContracts@
stanfordhealthcare.org

 

Download Gastrointestinal Pathology Requisition

SAMPLE SUBMISSION LOGISTICS
For more information on submitting cases, see the links below:

All Requisitions
Download Stanford Requisitions for specimen submission.

Account Set-up
Information on personalized requisitions, supplies, shipping and courier pick-up.

Pricing Inquiries
Pricing inquiries and contract information.

Billing
Billing policies, information and questions.

Results Web Portal
Request access or log-in to our client results portal.

Specimen Collection and Handling
Specifications for Specimen Collection and Handling.

Consult Service FAQ's
Get answers to Frequently Asked Questions.


close Submit a Specimen
Our Faculty

Teri A. Longacre, MD

Teri A. Longacre, MD

APPOINTMENTS

  • Professor of Pathology, Emerita Kempson Endowed Chair in Surgical Pathology
  • Director, Gastrointestinal-Hepatopancreatobiliary Pathology Service
  • Director, Gastrointestinal-Hepatopancreatobiliary Pathology Fellowship
  • Director, Gynecologic Pathology Service
  • Director, Gynecological Pathology Fellowship

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology
  • Gynecologic and Obstetric Pathology

CONTACT

Email: longacre@stanford.edu
Phone: (650) 498-6460

More information about Teri Longacre:
https://med.stanford.edu/profiles/teri-longacre

Gerald J. Berry, MD

Gerald Berry, MD

APPOINTMENTS

  • Professor of Pathology

 

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Cardiovascular Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology
  • Pulmonary & Thoracic Pathology

CONTACT

Email: gerald.berry@stanford.edu
Phone: (650) 498-4987

More information about Gerald Berry:
https://med.stanford.edu/profiles/gerald-berry

David Bingham, MD

David Bingham, MD

APPOINTMENTS

  • Clinical Assistant Professor, Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology

CONTACT

Phone: (650) 498-4391

More information about David Bingham:
https://med.stanford.edu/profiles/david-bingham

Lawrence Walden Browne, MD

Lawrence Walden Browne, MD

APPOINTMENTS

  • Clinical Assistant Professor of Pathology
    ValleyCare Tri-Valley

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology
  • Medical Liver Pathology

CONTACT

Email: waldenb@stanford.edu
Phone: (925) 416-3404

More information about Lawrence Browne:
https://med.stanford.edu/profiles/lawrence-browne

Gregory Charville, MD, PhD

Gregory Charville, MD, PhD

APPOINTMENTS

  • Associate Professor of Pathology
  • Medical Director, Soft Tissue and Bone Pathology Service
  • Associate Director of Gastrointestinal Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Bone-Soft Tissue Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology

CONTACT

Email: gwc@stanford.edu
Phone: (650) 723-7211

More information about Gregory Charville:
https://med.stanford.edu/profiles/greg-charville

John Higgins, MD

John Higgins, MD

APPOINTMENTS

  • Residency Program Director for Anatomic and Clinical Pathology
  • Professor of Pathology
  • Co-Director, Post-Sophomore Fellowship in Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology
  • Medical Liver Pathology
  • Renal Pathology
  • Transplant Pathology

CONTACT

Email: john.higgins@stanford.edu
Phone: (650) 723-7211

More information about John Higgins:
https://med.stanford.edu/profiles/john-higgins

Maggie Lam, MD

Maggie Lam, MD

APPOINTMENTS

  • Clinical Associate Professor of Pathology
    ValleyCare Medical Center
  • SHC Tri-Valley Director of Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Breast Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology

CONTACT

Email: mmlam@stanford.edu
Phone: (925) 416-3404

More information about Maggie Lam:
https://med.stanford.edu/profiles/maggie-lam

Richard Hildebrandt, MD

Richard Hildebrandt, MD

APPOINTMENTS

  • Clinical Assistant Professor, Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology
  • Obstetric Pathology

CONTACT

Email: rhildey8@stanford.edu
Phone: (650) 723-7211

More information about Richard Hildebrandt:
https://med.stanford.edu/profiles/richard-hildebrandt

Jody Hooper, MD

Donald P. Regula Jr., MD

APPOINTMENTS

  • Director of Autopsy, Director of Research Autopsy Center
  • Associate Professor – University Medical Line, Pathology
  • Member, Stanford Cancer Institute

PRACTICE AREAS

  • Anatomic Pathology
  • Autopsy
  • Gastrointestinal Pathology

CONTACT

Email: jehooper@stanford.edu  

Phone: (650) 723-6265

Jeanne Shen, MD

Jeanne Shen, MD

APPOINTMENTS

  • Assistant Professor of Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Digital Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology

CONTACT

Phone: (650) 723-7211

More information about Jeanne Shen:
https://med.stanford.edu/profiles/jeanne-shen

Serena Tan, MD

Serena Tan, MD

APPOINTMENTS

  • Assistant Professor of Pathology

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology
  • Pediatric Pathology

CONTACT

Phone: (650) 723-6111

More information about Serena Tan:
https://med.stanford.edu/profiles/serena-tan

Cindy Wang, MD

APPOINTMENTS

  • Clinical Assistant Professor of Pathology
  • Associate Director of Gastrointestinal-Hepatopancreatobiliary Pathology Fellowship

PRACTICE AREAS

  • Anatomic and Clinical Pathology
  • Gastrointestinal-Hepatopancreatobiliary Pathology

CONTACT

Email: cwang22@stanford.edu
Phone: (650) 498-4987

More information about Cindy Wang:
https://med.stanford.edu/profiles/252486


close Our Faculty
Ancillary Testing

Ancillary Testing

Stanford’s Gastrointestinal & Hepatobiliary Pathology Service relies on a suite of ancillary testing offerings to support our expert diagnosis. Learn more about these offerings. Many of these techniques, such as molecular profiling and cytogenetics, can be performed on cytology as well as tissue sections.

 

Immunohistochemistry

Our immunohistochemistry laboratory offers a wide array of antibody-based tests and in situ hybridization assays, which our pathologists select and interpret judiciously to refine their diagnoses.

These assays are validated for paraffin-embedded tissue, including cytology cell blocks. We provide testing for inflammatory myofibroblast tumor (ALK), MMR deficiency, pancreatic acinar cell carcinoma, and SDH deficiency, in addition to all the standard markers in gastrointestinal and hepatobiliary pathology (p53, p16, PDL-1, HER2, etc.). We also offer high-risk HPV in-situ hybridization.

 

Molecular Pathology

Molecular assays can be used for both diagnostic and prognostic purposes as well as for selection of targeted therapies. Stanford’s Solid Tumor Actionable Mutation Panel (STAMP) is validated on cytology specimens and paraffin-embedded tissue. We provide specific tests for various gastrointestinal mesenchymal lesions, including NTRK-rearranged sarcoma.

 

Cytogenetics

Cytogenetic studies are used to assess for chromosomal rearrangements in selected cases.


close Ancillary Testing

Residencies and Fellowships

Anatomic Pathology Residency Programs

Stanford Pathology offers a 3-year anatomic pathology residency and 4-year combination residencies in anatomic pathology/clinical pathology and anatomic pathology/neuropathology.Stanford Pathology offers a 3-year anatomic pathology residency and 4-year combination residencies in anatomic pathology/clinical pathology and anatomic pathology/neuropathology.

 

Gastrointestinal Pathology Fellowships

Stanford offers an ACGME-accredited fellowship in Gastrointestinal Pathology.

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